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Scientist Will Rodman is determined to find a cure for Alzheimer’s, the disease which has slowly consumed his father Charles. Will feels certain he is close to a breakthrough and tests his latest serum on apes, noticing dramatic increases in intelligence and brain activity in the primate subjects… Especially Caesar, his pet chimpanzee.
At the story’s heart is Caesar (Andy Serkis), a chimpanzee who gains human-like intelligence and emotions from an experimental drug. Raised like a child by the drug’s creator, Will Rodman (James Franco) and a primatologist Caroline Aranha (Freida Pinto), Caesar ultimately finds himself taken from the humans he loves and imprisoned in an ape sanctuary in San Bruno. Seeking justice for his fellow inmates, Caesar gives the fellow apes the same drug that he inherited. He then assembles a simian army and escapes the sanctuary – putting man and ape on a collision course that could change the planet forever.